Browse all practice questions for the NCLEX Hepatic and Biliary Practice Exam. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • Which statement best describes the storage site of bile?
  • Which condition is a consequence of portal hypertension that leads to fluid accumulation in the abdomen?
  • Which statement is true about acute vs chronic hepatitis infections?
  • In the setting of a balloon tamponade for variceal bleeding, which precaution is essential to ensure patient safety?
  • A patient with hepatitis develops hepatic encephalopathy. Which lab result best correlates with this mental status change?
  • In chronic pancreatitis, secondary diabetes results from dysfunction of which pancreatic cells?
  • A client with suspected biliary obstruction reports changes in stool color. Which stool color is common with biliary obstruction?
  • Which enzyme aids in the digestion of fats?
  • Which intervention would you expect to be prescribed for a client with acute pancreatitis to support pancreatic rest?
  • In advanced cirrhosis with hepatic encephalopathy, which assessment finding should the nurse report immediately?
  • Regarding the Hepatitis A vaccine, which statement is accurate?
  • The pungent, musty breath characteristic of advanced liver disease is called?
  • Which client statement is most consistent with vitamin C deficiency in chronic liver dysfunction?
  • What is the primary goal of nursing care for a client with acute pancreatitis?
  • In a client with pancreatitis, which condition necessitates close monitoring of fluid intake and output and electrolytes?
  • What is the BEST preventive measure to help prevent ALL types of viral Hepatitis?
  • Hepatitis D infection occurs only in conjunction with infection by which virus?
  • For a client with portal hypertension and esophageal varices, what is the goal of nursing interventions?
  • Which lab result would best explain hepatic encephalopathy signs such as disorientation and asterixis?
  • A client is scheduled for a cholecystogram. What is the diagnostic use of this exam?
  • In acute liver failure with confusion and decreased level of consciousness, which diagnostic finding best explains this behavior?
  • Which sign is commonly associated with hepatic encephalopathy due to ammonia buildup?
  • A patient with hepatic encephalopathy should avoid which meal option?
  • Which of the following is a function of the liver?
  • Which symptom will a nurse observe most commonly in clients with pancreatitis?
  • In common bile duct obstruction, which change occurs in urine coloration?
  • A patient with hepatitis has a bilirubin level of 6 mg/dL. Which finding would you expect?
  • A client being treated for pancreatitis faces the risk of atelectasis. Which intervention would be important to minimize this risk?
  • Kupffer cells reside in the liver and perform which function?
  • Which of the following is a sign commonly associated with hepatitis?
  • Which option below is a complication of portal hypertension?
  • Hepatitis B exposure postexposure prophylaxis (HBIG) should be given as soon as possible, preferably within how long after exposure?
  • During an acute episode of cholecystitis, where is the pain most likely located and radiating?
  • Hepatitis B immune globulin (HBIG) provides what type of protection?
  • Which phase is described as prodromal and precedes jaundice?
  • After an incisional cholecystectomy for cholelithiasis, which nursing intervention is the highest priority for the client?
  • In a client with cirrhosis and elevated ammonia, which diet is anticipated?
  • In managing ascites due to liver dysfunction, which monitoring measures are essential?
  • Lactulose reduces ammonia by which mechanism?
  • A patient with high bilirubin may present with which assessment finding?
  • Which statement about the liver’s production is true?
  • Which statement about hepatitis is correct?
  • A patient with cirrhosis is admitted; which vessel delivers blood high in nutrients to the liver?
  • In cirrhosis, collateral vessels reflect GI circulation changes. Which finding reflects this process?
  • Which statement about amylase in acute pancreatitis is correct?
  • Which type of hepatitis is transmitted by fecal-oral exposure, often from contaminated food?
  • An older client with cirrhosis on diuretic therapy shows a steady weight loss. Which of the following findings most likely indicates effective diuresis?
  • Which is NOT a function of the liver?
  • Which vessel carries nutrient-rich blood to the liver?
  • Which hepatitis is transmitted primarily through sexual contact and infected blood?
  • A patient with cirrhosis is at risk for esophageal variceal bleeding. Which finding would be most concerning?
  • In the icteric phase, which symptom is commonly present?
  • Which dietary instruction is appropriate for a patient with active Hepatitis B?
  • A client with cirrhosis has difficulty arousing and an elevated serum ammonia level. Which situation should the nurse suspect?
  • How is Hepatitis E transmitted?
  • Which sign indicates jaundice in a patient with liver disease?
  • After an upper abdominal surgery for gallbladder disease, which intervention best prevents respiratory complications?
  • For a client with viral hepatitis, what is the recommended daily fluid intake to support nutrition?
  • What does ERCP stand for?
  • Which hepatitis type currently has a preventive vaccine available in the United States?
  • Which type of hepatitis is transmitted by blood or body fluids?
  • A patient has a positive HBsAg. What education will you provide?
  • A patient with esophageal varices is at risk for hemorrhagic shock. Which sign indicates hypovolemia?
  • Why is a low-fat diet often recommended for patients with viral hepatitis?
  • Lactulose is prescribed to treat hepatic encephalopathy. Which lab result would indicate the medication was effective?
  • A client has begun medication therapy with pancrelipase (Pancrease MT). The nurse evaluates that the medication is having the optimal intended benefit if which effect is observed?
  • In what location would the nurse palpate for the liver?
  • Which statement best describes mild acute pancreatitis?
  • A physician orders spironolactone (Aldactone), 50 mg by mouth four times daily, for a client with fluid retention caused by cirrhosis. Which finding indicates that the drug is producing a therapeutic effect?
  • A patient with cirrhosis shows hand-flapping tremors. How is this finding documented?
  • Elevated ammonia with changes in mental status indicates which condition?
  • Which enzyme primarily digests carbohydrates and is secreted by the exocrine pancreas?
  • After completing the Hepatitis B vaccine series, which blood result demonstrates immunity?
  • Hepatitis G is most similar to which hepatitis?
  • In acute liver failure, which lab finding best explains the decreased level of consciousness?
  • Deficient vitamin K absorption due to hepatic disease presents with which assessment finding?
  • Which statement best describes the storage site of bile?
  • What is the predominant clinical feature of acute pancreatitis?
  • Infants who contract Hepatitis B at birth are at high risk for chronic infection. Which option reflects this scenario?
  • Which laboratory finding is most consistent with hyperammonemia-related encephalopathy?
  • Which phase follows the icteric phase and indicates recovery?
  • Which statement is true about lactulose therapy for hepatic encephalopathy?
  • A client scheduled for an endoscopic retrograde cholangiopancreatography (ERCP) asks what to expect. The nurse identifies the need for further information if the client says which statement?
  • If a patient tests positive for anti-HAV and IgG, what is the appropriate interpretation?
  • What is the most common route of transmission for Hepatitis A?
  • Which laboratory test is elevated to help confirm suspected pancreatitis?
  • Which statement correctly describes a total pancreatectomy?
  • If a patient has positive anti-HBs, what can be inferred?
  • What is the most common reason for inserting a nasogastric tube after abdominal surgery?
  • Cholecystojejunostomy is performed to relieve obstructive jaundice and is generally considered a palliative procedure. Which choice best reflects this statement?
  • Is a patient with Hepatitis A contagious before and after signs and symptoms?
  • What initial measure can the nurse implement to reduce risk of injury for a client with liver disease?
  • What is the purpose of balloon tamponade in esophageal variceal bleeding?
  • Which sign indicates hepatic encephalopathy?
  • During preoperative teaching, a client asks where bile is stored. The nurse knows that bile is stored in the:
  • When assessing a client with cirrhosis, which stool color is typically reported due to lack of bile in the GI tract?
  • Which finding indicates lactulose is effectively reducing ammonia in hepatic encephalopathy?
  • Which instruction should the nurse give a client with viral hepatitis to provide adequate nutrition?
  • Which of the following is NOT an expected outcome of pancrelipase therapy?
  • Which dietary consideration is appropriate for pancreatitis to minimize pancreatic stimulation?
  • Which laboratory pattern is most typical of hepatocellular injury in hepatitis?
  • Which pancreatic enzyme primarily digests fats?
  • Which neurological sign is most commonly associated with hepatic encephalopathy?
  • A client with severe chronic liver disease reports difficulty seeing at night. Which vitamin deficiency is most likely responsible?
  • After cholecystectomy with a T-tube, which drainage color indicates expected progression?
  • During assessment of a patient with cirrhosis and splenomegaly, which lab finding would you monitor most closely?
  • Asterixis is associated with hepatic encephalopathy. Which stage is typically linked to this finding?
  • In acute pancreatitis pain management, which intervention takes priority?
  • Which nursing intervention is most appropriate for a pancreatitis patient in the ICU?
  • Which statement about the liver’s role in coagulation is correct?
  • A postoperative client has a PRN order for ondansetron (Zofran). For which condition is this medication prescribed?
  • Which sign indicates hepatic encephalopathy due to ammonia buildup?
  • A physician orders for a new client with pancreatitis include bed rest, NPO, and total parenteral nutrition (TPN). What is the reason for the NPO status?
  • Which intervention helps prevent atelectasis and pooling of respiratory secretions in acute pancreatitis?
  • In the icteric phase, what happens to flu-like symptoms?
  • A patient with continued variceal bleeding after pharmacologic and endoscopic therapy requires a procedure that lowers portal pressure. Which procedure is indicated?
  • A lab shows positive HBsAg. Which education would be appropriate?
  • A client has a T-tube drainage of 750 mL since cholecystectomy. What is the most appropriate nursing action?
  • During the posticteric phase, what happens to liver enzymes and bilirubin?
  • Which of the following statements is a sign of jaundice?
  • For Hepatitis A, contagiousness occurs before symptoms and continues after symptoms.
  • A client is undergoing removal of the head of the pancreas, resection of the duodenum and stomach, with redirecting the flow of secretions from the stomach, gallbladder, and pancreas into the jejunum. What procedure is this client undergoing?
  • Esophageal varices are almost always caused by which hepatobiliary condition?
  • In cirrhosis, decreased metabolism of estrogen may lead to which finding?
  • Which procedure removes the bottom half of the pancreas?
  • Which statement about esophageal varices is true?
  • A client newly prescribed cholestyramine (Questran). Which statement indicates a need for further instruction?
  • Clinical manifestations of common bile duct obstruction include all of the following except?
  • The liver receives two blood supplies; which vessel delivers oxygen-rich arterial blood to the liver?
  • Which description best characterizes the pain in acute pancreatitis?
  • A patient is prescribed Peginterferon alfa-2a. What route is appropriate for administration?
  • Which patient below is at MOST risk for developing a complication related to a Hepatitis E infection?
  • To prevent hypokalemia in a patient with ascites, which diuretic is potassium-sparing and may be ordered?
  • A client reports severe right shoulder pain 24 hours after laparoscopic cholecystectomy. Which statement provides correct information for the nurse to convey?
  • How should the nurse assess for the presence of asterixis in a client with cirrhosis?
  • A patient with gross ascites is positioned in high semi-Fowler’s. What is the nurse’s priority assessment for this patient?
  • A client has hepatitis A after eating contaminated oysters. Which assessment finding would you expect?
  • A patient exposed to Hepatitis A at a restaurant one week ago: what education is important?
  • Which type of deficiency results in macrocytic anemia?
  • Which phase is prodromal with flu-like symptoms such as fatigue and nausea?
  • The liver receives blood from two sources. Which vessel delivers blood high in nutrients but low in oxygen to the liver?
  • Which position is most helpful to ease abdominal pain in a patient with acute pancreatitis?
  • Select the bilirubin level that would be considered normal in the context of hepatitis.
  • Lactulose is used in cirrhosis to detoxify ammonium and act as an osmotic laxative. Which statement best describes its action?
  • What is the treatment approach for Hepatitis A?
  • Which statement best describes the storage site of bile?
  • Chronic pancreatitis with increased appetite and thirst may indicate secondary diabetes. What explains the cause?
  • Which phase is associated with prodromal signs before jaundice appears?
  • Drug-induced hepatitis is a major cause of acute liver failure. Which medication is the leading cause?
  • If anti-HAV and IgM are detected, what does that indicate?
  • A nurse is providing dietary instructions to a client with a history of pancreatitis. Which instruction is correct?
  • A 45-year-old man with cirrhosis develops gynecomastia. Which explanation is correct?
  • Which phase features a hallmark sign of hepatitis?
  • Which is an age-related change of the hepatobiliary system?
  • A client with massive esophageal variceal hemorrhage requires balloon tamponade. What is the highest-priority goal in planning care?
  • A client with cirrhosis has elevated ammonia. Which medication will the nurse administer to detoxify ammonium and act as an osmotic agent?
  • Which phase is also called the posticteric phase?
  • Which statement best describes fluid management in pancreatitis?
  • A patient with acute pancreatitis has an order for an anticholinergic medication. This medication is given to which purpose?
  • A patient with severe chronic liver dysfunction presents with gingival bleeding and blood in the stool. Which vitamin deficiency is most likely?
  • How many lobes does the liver have?
  • A patient with esophageal varices is at risk for hemorrhagic shock. Which sign indicates potential hypovolemia?
  • In which phase would you expect bilirubin and liver enzymes to normalize after the acute illness?
  • Which statement is correct about hepatitis vaccines options in the United States?
  • A critical care nurse is caring for a client with acute pancreatitis. Which of the following would be an appropriate intervention to prevent respiratory complications?
  • What test should the nurse prepare the client for that will locate stones in the common bile duct?
  • Which phase features clay-colored stool due to bilirubin not reaching the stool?
  • In the posticteric phase, which statement best describes jaundice and stool color?
  • When should the second and third doses of the hepatitis B vaccine be administered?
  • Upon receiving a dinner tray for a patient admitted with acute gallbladder inflammation, which item should be questioned?
  • Prevention of Hepatitis D includes vaccination against which virus?
  • For a patient evaluated with acute cholecystitis and biliary colic, which nursing diagnosis takes top priority?
  • Which phase of hepatitis is characterized by jaundice and dark urine?
  • What nursing assessment should be performed when the abdomen is distended in cirrhosis?
  • In acute pancreatitis, guarding and a board-like abdomen is an ominous sign and usually indicates which complication?
  • What is the most common transmission route of Hepatitis C?
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